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Journal of the American Animal Hospital Association, Vol 31, Issue 4, 295-299
Copyright © 1995 by American Animal Hospital Association

Articles

Canine immune-mediated diabetes mellitus: a case report

M Elie and M Hoenig

A four-year-old, spayed female toy fox terrier presented with hyperglycemia and severe anemia. A diagnosis of immune-mediated diabetes mellitus was made based upon the finding of beta-cell specific antibodies. Immune-mediated hemolytic anemia was diagnosed based on findings of a regenerative anemia, spherocytosis, hyperbilirubinemia, hemoglobinuria, and bilirubinuria. The anemia resolved following two months of immunosuppressive therapy. The diabetes was treated with insulin for four months, after which time treatment was no longer necessary. However, the dog remained positive for beta-cell antibodies which may be a predictive marker for the recurrence of diabetes mellitus in the future.


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J. S. Rand, L. M. Fleeman, H. A. Farrow, D. J. Appleton, and R. Lederer
Canine and Feline Diabetes Mellitus: Nature or Nurture?
J. Nutr., August 1, 2004; 134(8): 2072S - 2080S.
[Abstract] [Full Text] [PDF]


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