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Journal of the American Animal Hospital Association, Vol 32, Issue 3, 257-262
Copyright © 1996 by American Animal Hospital Association

Articles

Canine mandibular osteosarcoma: 51 cases (1980-1992)

RC Straw, BE Powers, J Klausner, RA Henderson, WB Morrison, DL McCaw, HJ Harvey, RM Jacobs, and RJ Berg

Fifty-one dogs treated for mandibular osteosarcomas (OSs) were studied retrospectively. Treatments were partial mandibulectomy (n = 32); partial mandibulectomy and chemotherapy (n = 10); partial mandibulectomy and radiation therapy (n = 3); partial mandibulectomy, radiation therapy, and chemotherapy (n = 4); and radiation therapy alone (n = 2). The overall one-year survival rate was 59.3%. Dogs treated with surgery alone had a one-year survival rate of 71%, which is higher than the one-year survival rate for dogs with appendicular OSs treated with surgery alone (p of 0.001 or less; hazard ratio of 0.29). There was no apparent effect of various treatment modalities, nor institution where treatment was given, nor histological type. Histological score and, to a lesser extent, histological grade were predictive of survival outcome.


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