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Journal of the American Animal Hospital Association, Vol 35, Issue 1, 33-35
Copyright © 1999 by American Animal Hospital Association

Articles

Cyanosis and congenital methemoglobinemia in a puppy

DM Fine, GE Eyster, LK Anderson, and A Smitley

A six-month-old Pomeranian was referred for evaluation of cyanosis. The puppy had been cyanotic since it was acquired at six weeks of age, but otherwise appeared normal. Diagnostics were aimed at the most common causes (i.e., congenital defects in the cardiovascular and respiratory systems) of cyanosis in a juvenile animal. No clinically significant abnormalities were detected on evaluation of thoracic radiographs, echocardiogram, cardiac color-flow Doppler examination, or blood gases. At this point, a dysfunction in hemoglobin was considered as a possibility. Methemoglobinemia due to deficiency of methemoglobin reductase enzyme was diagnosed based on a specific assay.


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K. P. Wallace, S. A. Center, F. H. Hickford, K. L. Warner, and S. Smith
S-Adenosyl-L-Methionine (SAMe) for the Treatment of Acetaminophen Toxicity in a Dog
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