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Journal of the American Animal Hospital Association, Vol 35, Issue 1, 48-51
Copyright © 1999 by American Animal Hospital Association

Articles

Iatrogenic Cushing's syndrome and steroid hepatopathy in a cat

M Schaer and PE Ginn

The distinguishing clinical features of Cushing's syndrome in the cat include very friable skin, a high incidence of diabetes mellitus, and the general absence of steroid hepatopathy. This case report describes a nine-year-old, spayed female domestic shorthair with triamcinolone-induced Cushing's syndrome. Unique to this cat were markedly elevated liver enzymes which prompted an expanded clinical evaluation. An ultrasonographic-guided liver biopsy demonstrated diffuse hepatocellular vacuolation that stained periodic acid-Schiff (PAS) positive and was removed subsequently with diastase application, indicating glycogen accumulation. These findings are compatible with the rarely seen syndrome of steroid hepatopathy in the cat.


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Y.-H. Lien, H.-P. Huang, and P.-H. Chang
Iatrogenic hyperadrenocorticism in 12 cats.
J. Am. Anim. Hosp. Assoc., November 1, 2006; 42(6): 414 - 423.
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