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Journal of the American Animal Hospital Association, Vol 35, Issue 3, 200-207
Copyright © 1999 by American Animal Hospital Association

Articles

Iatrogenic hyperadrenocorticism in 28 dogs

HP Huang, HL Yang, SL Liang, YH Lien, and KY Chen

Twenty-eight dogs with iatrogenic hyperadrenocorticism were studied. The most common clinical signs were cutaneous lesions (27/28), polydipsia (21/28), polyuria (19/28), and lethargy (16/28). The most predominant findings on biochemical profile were elevated alkaline phosphatase (ALP, 15/28) and alanine transferase (ALT, 14/28); hypercholesterolemia (14/28); elevated aspartate transferase (AST, 12/28); and elevated triglycerides (12/18). Baseline cortisol levels of all 28 dogs were at the lower end of the reference range and exhibited suppressed or no response to adrenocorticotropic hormone (ACTH) stimulation. The mean time for each dog to show initial improvement of clinical signs after corticosteroid withdrawal was six weeks, with another mean time of 12 weeks to demonstrate complete remission.


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Y.-H. Lien, H.-P. Huang, and P.-H. Chang
Iatrogenic hyperadrenocorticism in 12 cats.
J. Am. Anim. Hosp. Assoc., November 1, 2006; 42(6): 414 - 423.
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