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Journal of the American Animal Hospital Association, Vol 35, Issue 4, 279-283
Copyright © 1999 by American Animal Hospital Association


Articles

Use of echocardiography in the diagnosis of dilated cardiomyopathy in Irish wolfhounds

AC Vollmar

The purpose of this study was to compare the echocardiographic features of Irish wolfhounds with clinically inapparent dilated cardiomyopathy (DCM) (n = 33) to dogs with advanced DCM (n = 33) and to normal dogs (n = 262). Significant differences were detected between the three groups. In dogs with DCM, the most sensitive diagnostic measurements were: end-systolic volume index (ESVI), E-point to septal separation (EPSS), fractional shortening (FS), and left ventricular internal dimensions (LVIDd and LVIDs). Left atrial diameter was increased markedly in dogs with DCM and 83.3% of affected Irish wolfhounds had concurrent atrial fibrillation. Compared with early DCM, in advanced DCM there was a significant increase in end-diastolic right ventricular diameter, often combined with extensive pleural effusion, the leading sign of congestive heart failure in Irish wolfhounds.


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J HeredHome page
U. Philipp, C. Broschk, A. Vollmar, and O. Distl
Evaluation of Tafazzin as Candidate for Dilated Cardiomyopathy in Irish Wolfhounds
J. Hered., July 9, 2007; (2007) esm045v1.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
B. J. Biesiadecki, B. D. Elder, Z.-B. Yu, and J.-P. Jin
Cardiac Troponin T Variants Produced by Aberrant Splicing of Multiple Exons in Animals with High Instances of Dilated Cardiomyopathy
J. Biol. Chem., December 20, 2002; 277(52): 50275 - 50285.
[Abstract] [Full Text] [PDF]




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