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Journal of the American Animal Hospital Association, Vol 35, Issue 6, 475-481
Copyright © 1999 by American Animal Hospital Association


Articles

Long-term case study of myelodysplastic syndrome in a dog

T Miyamoto, T Horie, T Shimada, M Kuwamura, and E Baba

A 10-year-old, female shih tzu was diagnosed as having myelodysplastic syndrome (MDS) based on the presence of a nonregenerative anemia, dysplastic changes in the three hematopoietic cell lines, a normal to hypercellular bone marrow, and less than 30% blast cells of all nucleated cells in the bone marrow. Low-dose aclarubicin, a differentiation-induction therapy for MDS and atypical leukemias in humans, was administered. Hematological improvement was observed, and the dog lived for 809 days after the first presentation.


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Toxicol PatholHome page
J. T. Blue
Myelodysplasia: Differentiating Neoplastic from Nonneoplastic Syndromes of Ineffective Hematopoiesis in Dogs
Toxicol Pathol, January 1, 2003; 31(1_suppl): 44 - 48.
[Abstract] [PDF]




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