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Journal of the American Animal Hospital Association, Vol 37, Issue 5, 461-465
Copyright © 2001 by American Animal Hospital Association

Articles

Histiocytic ulcerative colitis in three non-boxer dogs

JE Stokes, JM Kruger, T Mullaney, K Holan, and W Schall

Histiocytic ulcerative colitis (HUC) is described in three non-boxer dogs. Clinical signs were typical of large-bowel diarrhea and included soft stool, hematochezia, tenesmus, and an increased frequency of defecation. Diagnosis in each case was made by light microscopic evaluation of endoscopically obtained colonic biopsy specimens. Treatment regimes varied, but included immunosuppressive agents, anti-inflammatory drugs, antimicrobials, and dietary modification. Clinical response was substantial in two patients, while the third patient was euthanized due to treatment failure. The authors' observations indicate that HUC may be encountered in non-boxer dogs.


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