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Journal of the American Animal Hospital Association 38:415-419 (2002)
© 2002 American Animal Hospital Association

Case Report

Cutaneous Neosporosis During Treatment of Pemphigus Foliaceus in a Dog

Laura Ordeix, DVM, Albert Lloret, DVM, Dolors Fondevila, DVM, PhD, Diplomate ECVP, J. P. Dubey, BVSc & AH, MVSc, PhD, Lluís Ferrer, DVM, PhD, Diplomate ECVD and Alessandra Fondati, DVM, Diplomate ECVD

From the Department de Medicina i Cirurgia Animal (Ordeix, Fondevila, Ferrer, Fondati) and the Hospital Clínic Veterinari (Lloret), Veterinary School, Universitat Autònoma de Barcelona, Bellaterra 08193 Spain and the Parasite Biology, Epidemiology, and Systematics Laboratory (Dubey), USDA, ARS, ANRI, Beltsville, Maryland 20705-2350.

A 4-year-old, intact male rottweiler was presented with a 10-day history of papulonodular dermatitis. At the time of presentation, the dog was receiving prednisone and azathioprine to treat pemphigus foliaceus. Cutaneous neosporosis was diagnosed by immunohistochemistry on skin biopsy specimens and a high serum antibody titer to Neospora caninum by Neospora agglutination test. Electron microscopy examination of skin specimens further supported the diagnosis. Clindamycin therapy, together with withdrawal of immunosuppressive medication, resulted in prolonged clinical remission. This report documents cutaneous neosporosis in an adult dog and suggests that immunosuppressive therapy might be a predisposing factor.




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J. A. Webb, S. L. Keller, E. P. Southorn, J. Armstrong, D. G. Allen, A. S. Peregrine, and J.P. Dubey
Cutaneous Manifestations of Disseminated Toxoplasmosis in an Immunosuppressed Dog
J. Am. Anim. Hosp. Assoc., May 1, 2005; 41(3): 198 - 202.
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Copyright © 2002 by the American Animal Hospital Association.