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Treatment of Renal Nephroblastoma in an Adult Dog

From the Departments of Small Animal Clinical Sciences (Seaman) and Pathology (Patton), College of Veterinary Medicine, University of Tennessee, Box 1071, Knoxville, Tennessee 37901-1071.

An 8-year-old Labrador retriever was diagnosed with a unilateral malignant nephroblastoma and hypertrophic osteopathy. The histopathologically malignant tumor was confined to the renal capsule, but the sarcomatous component was anaplastic, resulting in its classification as a Stage I tumor with unfavorable histopathology. The dog was treated with unilateral nephrectomy, vincristine, and doxorubicin. This dog has remained disease free for >25 months. Reported treatments of renal nephroblastoma in the dog have not described disease-free intervals of >8 months.

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				A. M. Gasser, W. W. Bush, S. Smith, and R. Walton Extradural Spinal, Bone Marrow, and Renal Nephroblastoma J. Am. Anim. Hosp. Assoc., January 1, 2003; 39(1): 80 - 85. [Abstract] [Full Text] [PDF]