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Journal of the American Animal Hospital Association 39:86-89 (2003)
© 2003 American Animal Hospital Association

Retrospective Study

Efficacy of Cobalt-60 Radiation Therapy for the Treatment of Nasal Cavity Nonkeratinizing Squamous Cell Carcinoma in the Dog

Stephanie Shank Correa, DVM, Diplomate ACVIM (Oncology), G. Neal Mauldin, DVM, Diplomate ACVIM (Internal Medicine Oncology), Diplomate ACVR (Radiation Oncology), Glenna E. Mauldin, DVM, MS, Diplomate ACVIM (Oncology) and Amiya K. Patnaik, BVSc, MVSc

From the Department of Veterinary Clinical Sciences (Correa, Mauldin, Mauldin), School of Veterinary Medicine, Louisiana State University, South Stadium Drive, Baton Rouge, Louisiana 70803 and the Department of Pathology (Patnaik), The Elmer and Mamdouha Bobst Hospital of The Animal Medical Center, 510 East 62nd Street, New York, New York 10021.

The purposes of this study were to evaluate the efficacy of cobalt-60 radiotherapy in the treatment of nonkeratinizing squamous cell carcinoma of the nasal cavity in dogs and to compare this treatment group to historical controls. Six dogs with histopathologically confirmed nasal cavity nonkeratinizing squamous cell carcinoma were treated with cobalt-60 radiotherapy to a total dose of either 63 Gy or 54 Gy. Overall survival times ranged from 30 days to 330 days, with a median survival time of 165 days. Nasal cavity nonkeratinizing squamous cell carcinoma in the dog is an aggressive tumor that responds poorly to radiotherapy.






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Copyright © 2003 by the American Animal Hospital Association.