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Journal of the American Animal Hospital Association 39:139-150 (2003)
© 2003 American Animal Hospital Association

Retrospective Study

A Retrospective Study Regarding the Treatment of Lupoid Onychodystrophy in 30 Dogs and Literature Review

Ralf S. Mueller, Dr.med.vet., Diplomate ACVD, Rodney A. W. Rosychuk, DVM, Diplomate ACVIM and Leonard D. Jonas, DVM, Diplomate ACVIM

From the Animal Skin and Allergy Clinic (Mueller until 1999), 70 Blackburn Road, Mount Waverley, Victoria 3149, Australia; the Department of Clinical Sciences (Rosychuk, Mueller since 1999), College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80523; and Denver Veterinary Specialists (Jonas), 3695 Kipling Street, Wheat Ridge, Colorado 80033.

The treatment records of 30 dogs with lupoid onychodystrophy were evaluated retrospectively. Dogs were treated with fatty acid supplementation (n=18), doxycycline and niacinamide (n=12), tetracycline and niacinamide (n=10), pentoxifylline (n=6), prednisolone (n=5), azathioprine (n=1), clofazimine (n=1), or with combinations thereof. An excellent response was seen in almost half of the patients treated with tetra- or doxycycline in combination with niacinamide. Six of the dogs were maintained successfully on fatty acid supplementation. Spontaneous remissions and recurrences made evaluation of success rates difficult and emphasized the varied and often unclear etiology and natural course of the syndrome.






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Copyright © 2003 by the American Animal Hospital Association.