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Effects of Diet on Urine Composition of Cats With Calcium Oxalate Urolithiasis

From the Minnesota Urolith Center (Lulich, Osborne, Lekcharoensuk), College of Veterinary Medicine, University of Minnesota, Saint Paul, Minnesota 55108; Hill’s Science and Technology Center (Kirk), Topeka, Kansas 66601; and the Department of Small Animal Clinical Sciences, College of Veterinary Medicine (Bartges), University of Tennessee, Knoxville, Tennessee 37996.

Ten client-owned cats with calcium oxalate (CaOx) urolithiasis were evaluated to determine the effect of diet on urine CaOx saturation. Two dietary treatments were evaluated in each cat: the diet consumed just prior to urolith detection and a canned diet formulated to prevent CaOx uroliths. This study revealed that hypercalciuria is a consistent abnormality in cats with CaOx urolith formation. When urolith-forming cats consumed a diet formulated to prevent urolith formation, activity product ratios for CaOx (which estimate the degree to which urine is saturated with CaOx) were significantly lower. These results suggest that consumption of an appropriately formulated urolith-prevention diet will reduce recurrence of CaOx urolithiasis.