HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Ricci Lucas, S. R. Articles by de Benedetto Pozzi, D. H. Search for Related Content PubMed PubMed Citation Articles by Ricci Lucas, S. R. Articles by de Benedetto Pozzi, D. H.

Carmustine, Vincristine, and Prednisone in the Treatment of Canine Lymphosarcoma

From the Faculdade de Medicina, Veterinária e Zootecnia, (Lucas, Coelho, Marquezi, Franchini, Miyashiro) and Faculdade de Medicina (Pozzi), da Universidade de São Paulo, Brazil.

A chemotherapeutic protocol using carmustine in combination with vincristine and prednisone was tested in dogs with multicentric malignant lymphosarcoma. Of seven dogs treated, six (85.7%) achieved complete remission. A partial response occurred in one dog. Median survival time was 224 days (mean 386 days), and median duration of remission was 183 days (mean 323 days). Marked neutropenia was observed following carmustine administration. There were no significant alterations in platelets and red blood cell counts during treatment, and no abnormalities attributable to the chemotherapy were found in serum biochemical profiles. Results of this study showed that carmustine is an effective alternative option in the treatment of canine lymphosarcoma.