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Journal of the American Animal Hospital Association 41:68-73 (2005)
© 2005 American Animal Hospital Association


Case Report

Heinz Body Hemolytic Anemia With Eccentrocytosis From Ingestion of Chinese Chive (Allium tuberosum) and Garlic (Allium sativum) in a Dog

Osamu Yamato, DVM, PhD, Ei Kasai, DVM, Taro Katsura, DVM, Shinichi Takahashi, DVM, Takuji Shiota, DVM, Motoshi Tajima, DVM, PhD, Masahiro Yamasaki, DVM, PhD and Yoshimitsu Maede, DVM, PhD

From the Laboratory of Internal Medicine, Department of Veterinary Clinical Sciences, (Yamato, Kasai, Shiota, Yamasaki, Maede), and Veterinary Teaching Hospital (Tajima), Graduate School of Veterinary Medicine, Hokkaido University, Kita-ku, Sapporo 060-0818, Japan; and Katsura Animal Hospital (Katsura, Takahashi), Nishi-ku, Sapporo 063-0866, Japan.

A 4-year-old, intact male miniature schnauzer was presented with anorexia. The dog had ingested some Chinese steamed dumplings 2 days before, which contained Chinese chive (Allium tuberosum) and garlic (Allium sativum). Hematological examinations revealed severe Heinz body hemolytic anemia with eccentrocytosis and an increased concentration of methemoglobin, which was thought to result from oxidative damage to erythrocytes by constituents in these Allium plants. In this case, eccentrocytosis was a hallmark finding and could be detected easily, suggesting that this hematological abnormality is useful in diagnosing Allium plant-induced hemolysis.




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R. E. Gompf
Nutritional and Herbal Therapies in the Treatment of Heart Disease in Cats and Dogs
J. Am. Anim. Hosp. Assoc., November 1, 2005; 41(6): 355 - 367.
[Abstract] [Full Text] [PDF]




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