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Journal of the American Animal Hospital Association 41:292-297 (2005)
© 2005 American Animal Hospital Association


Review Article

Feline Acromegaly: A Review of the Syndrome

Charles A. Hurty, DVM and Bente Flatland, DVM, Diplomate ACVIM

From the Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, Georgia 30602.

Address all correspondence to Dr. Flatland.

Acromegaly is characterized by chronic excessive growth hormone (GH) secretion by the pituitary gland. Feline acromegaly is most commonly caused by a functional pituitary tumor. Definitive diagnosis can be difficult because of the gradual disease onset, subtle clinical signs, unavailability of relevant laboratory tests, and client financial investment. The most significant clinical finding of acromegaly is the presence of insulin-resistant diabetes mellitus. Diagnosis is currently based upon brain imaging and measurement of serum GH and/or insulin-like growth factor-1 concentrations. Definitive treatment in cats is not well described, but radiation therapy appears promising.







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