HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Kemppainen, R. J. Articles by Busch, K. A. Search for Related Content PubMed PubMed Citation Articles by Kemppainen, R. J. Articles by Busch, K. A.

Use of Compounded Adrenocorticotropic Hormone (ACTH) for Adrenal Function Testing in Dogs

From the Department of Anatomy, Physiology, and Pharmacology (Kemppainen, Busch) and the Department of Clinical Sciences (Behrend), College of Veterinary Medicine, Auburn University, Auburn, Alabama 36849.

Serum cortisol concentrations were measured in five healthy dogs in response to five adrenocorticotropic hormone (ACTH) preparations. Cortisol concentrations were similar at time 0 (pre-ACTH) and at 30 and 60 minutes after injection of all forms of ACTH. However, at 90 and 120 minutes post-ACTH, serum cortisol concentrations were significantly lower following injection of two compounded forms of ACTH. The data showed that injection of four compounded forms of ACTH caused elevations in serum cortisol concentrations of a similar magnitude as cosyntropin in samples collected 60 minutes after administration; but concentrations at later times varied, depending on the type of ACTH used.