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Clinical Efficacy of Selamectin in the Treatment of Naturally Acquired Infection of Sucking Lice (Linognathus setosus) in Dogs

From the Department of Parasitology (Gunnarsson, Christensson), National Veterinary Institute, SE-751 89 Uppsala, Sweden and the Department of Small Animal Clinical Sciences (Palmér), Box 7037, Swedish University of Agricultural Sciences, SE-750 07 Uppsala, Sweden.

A clinical study was performed in 21 dogs to evaluate the efficacy of selamectin for the treatment of naturally acquired infection of sucking lice (Linognathus setosus [L.setosus]) in dogs. Each dog was randomly assigned to one of two treatment groups. One group was treated with selamectin applied topically at a mean dosage of 7.9 mg/kg. The other group was treated with permethrin applied topically at a mean dosage of 85.7 mg/kg. At day 42 posttreatment, all animals remaining in the study (10 treated with selamectin and six with permethrin) were clear of lice. In both groups, the reduction in lice counts from pretreatment values to day 42 was statistically significant at P0.0001. Selamectin applied topically appeared to be effective against L. setosus infection in dogs.