Journal of the American Animal Hospital Association 42:302-307 (2006)
© 2006 American Animal Hospital Association
Use of Posaconazole in the Management of Invasive Orbital Aspergillosis in a Cat
Gillian J. McLellan, BVMS, PhD, Diplomate ECVO, Diplomate ACVO,
Susette M. Aquino, DVM, Diplomate ACVO,
David R. Mason, BVetMed,
Joann M. Kinyon, MS and
Ronald K. Myers, DVM, PhD, Diplomate ACVP
From the Departments of Veterinary Clinical Sciences (McLellan, Aquino, Mason), Veterinary Diagnostic and Production Animal Medicine (Kinyon), and Veterinary Pathology (Myers), College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011-1250.
Orbital infection with Aspergillus fumigatus was diagnosed in a Persian cat that was presented with chronic third eyelid protrusion and exophthalmos. Evidence of nasal, sinus, or disseminated aspergillosis was not detected in this cat. Complete surgical excision of diseased tissues was not possible during orbital exenteration, and infection subsequently extended into the tissues of the oral cavity. Oral therapy with itraconazole and parenteral therapy with amphotericin B were ineffective in resolving the infection. Oral therapy with a novel triazole, posaconazole, was curative.
Copyright © 2006 by the American Animal Hospital Association.
