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Iatrogenic Hyperadrenocorticism in 12 Cats

From the Department of Veterinary Medicine, (Lien, Huang, Chang), National Taiwan University, No. 1, Section 4, Roosevelt Road, Taipei, 106, Taiwan and the Azu Clinic for Animals (Lien), 92, Section 1, Kin-Shan South Road, Taipei, 100, Taiwan.

Address all correspondence to Dr. Huang.

Iatrogenic hyperadrenocorticism is an extremely rare condition in cats. Twelve cats with a medical history of progressive skin lesions and long-term treatment with corticosteroids were retrospectively studied. Noncutaneous signs in the cats were variable and included anorexia, lethargy, polydipsia, polyuria, and atrophy of the thigh muscles. Laboratory abnormalities included leukocytosis, elevated alanine aminotransferase levels, and hyperglycemia. Transient diabetes mellitus was a secondary complication in four cats, and transient hypothyroidism was suspected in four cats. The mean time for regression of signs was 4.9 months after corticosteroid withdrawal.