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Long-Term Outcomes in Dogs With Sinonasal Aspergillosis Treated With Intranasal Infusions of Enilconazole

From the Department of Clinical Sciences, ULG–Faculty of Veterinary Medicine, Bld de Colonster, 20 – B44, Sart Tilman, 4000 Liège, Belgium.

Address all correspondence to Dr. Clercx.

Long-term outcomes (mean 38±17 months) were evaluated in 27 dogs with sinonasal aspergillosis after successful medical treatment using intranasal infusions of 1% or 2% enilconazole (1%, n=15; 2%, n=12). Long-term outcomes with both treatment protocols were good, with half of the dogs being asymptomatic throughout the follow-up period. The remaining dogs showed mild clinical signs compatible with chronic rhinitis/sinusitis. These clinical signs were interpreted as chronic lymphoplasmacytic rhinitis/sinusitis and episodes of bacterial rather than fungal infection. Three dogs had confirmed reinfection or relapse 2 to 36 months after clinical resolution.