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Journal of the American Animal Hospital Association 43:122-127 (2007)
© 2007 American Animal Hospital Association


Case Report

Giant Hypertrophic Gastritis (Ménétrier’s-like Disease) in an Old English Sheepdog

Tim S. Rallis, DVM, PhD, Michael N. Patsikas, DVM, PhD, Diplomate ECVDI, Mathios E. Mylonakis, DVM, PhD, Michael J. Day, BSc, BVMS (Hons), PhD, Diplomate ECVP, Theodoros A. Petanides, DVM, Lysimachos G. Papazoglou, DVM, PhD and Alexander F. Koutinas, DVM, PhD, Diplomate ECVD

From the Clinic of Companion Animal Medicine (Rallis, Mylonakis, Petanides, Koutinas) and the Clinic of Surgery (Patsikas, Papazoglou), School of Veterinary Medicine, Aristotle University of Thessaloniki, 11, St Voutyra str, 54627 Thessaloniki, Greece and the Division of Veterinary Pathology, Infection and Immunity (Day), School of Clinical Veterinary Science, University of Bristol, Langford, BS40 5DU United Kingdom.

Address all correspondence to Dr. Mylonakis.

An 11-year-old, male Old English sheepdog was admitted for weight loss and intermittent vomiting of 1 month’s duration. A cranioventral abdominal mass, anemia, hypoproteinemia, and hypoalbuminemia were the prominent abnormal findings. Imaging studies identified a remarkably thickened gastric wall with multilobulated folds protruding into the gastric lumen. Gastrotomy revealed the presence of giant cerebriform rugal folds arising from the fundus and body of the stomach. Pronounced gastric glandular hyperplasia and lack of evidence of cellular atypia were suggestive of giant hypertrophic gastritis. The dog was treated with prednisolone, cimetidine, and hyoscine butylbromide, only to experience a short-term remission.







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Copyright © 2007 by the American Animal Hospital Association.