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Journal of the American Animal Hospital Association 44:25-31 (2008)
© 2008 American Animal Hospital Association

Case Report

Aplastic Anemia in Two Kittens Following a Prescription Error

April L. Paul, DVM, Scott P. Shaw, DVM, Diplomate ACVECC and Carsten Bandt, DVM

From the Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, 200 Westboro Road, North Grafton, Massachusetts 01536.

A medication error resulted in two kittens being treated with azathioprine (12 and 12.5 mg/kg) instead of azithromycin for 2 weeks. On clinical examination, the kittens were febrile, weak, and had oronasal hemorrhage. Complete blood cell counts indicated severe bone marrow suppression. Treatment consisted of multiple transfusions, antibiotics, and granulocyte colony-stimulating factor. One of the kittens responded to therapy and had a complete recovery. The other kitten was treated for 40 days with no clinical response before dying. Both kittens also contracted Mycoplasma hemofelis infection from a contaminated blood transfusion.






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Copyright © 2008 by the American Animal Hospital Association.