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Malignant Peripheral Nerve Sheath Tumor of the Diaphragm in a Dog

From the Department of Small Animal Clinical Sciences (Patterson, Perry) and the Diagnostic Center for Population and Animal Health (Steficek), College of Veterinary Medicine, Michigan State University, East Lansing, Michigan 48824.

An 11-year-old, castrated male greyhound was referred to the Michigan State University Veterinary Teaching Hospital for surgical removal of a thoracic mass. Thoracic radiographs revealed a smoothly marginated mass obscuring the diaphragm in the left caudal thorax. Ultrasonographic and computed tomographic imaging modalities demonstrated a mass originating from the left hemidiaphragm. The mass was surgically removed and submitted for histopathological evaluation. Histopathology and immunohistochemical staining confirmed a malignant peripheral nerve sheath tumor.