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Journal of the American Animal Hospital Association 44:100-108 (2008)
© 2008 American Animal Hospital Association


Retrospective Study

Four-Fraction Radiation Therapy for Macroscopic Soft Tissue Sarcomas in 16 Dogs

Jessica Lawrence, DVM, Diplomate ACVR (Radiation Oncology), Lisa Forrest, VMD, Diplomate ACVR (Radiology, Radiation Oncology), William Adams, DVM, Diplomate ACVR (Radiology, Radiation Oncology), David Vail, DVM, Diplomate ACVIM (Oncology) and Douglas Thamm, VMD, Diplomate ACVIM (Oncology)

From the Departments of Surgical Sciences (Lawrence, Forrest, Adams) and Medical Sciences (Vail, Thamm), School of Veterinary Medicine, University of Wisconsin-Madison, 2015 Linden Drive, Madison, Wisconsin 53706.

A retrospective study of 16 dogs with macroscopic soft tissue sarcomas was performed to evaluate response to a four-fraction radiotherapy protocol (prescribed dose of 32 Gy). Radiation was well tolerated with minimal side effects. The overall response rate was 50%, with seven partial responses and one complete response. The median time to progression was 155 days, and the median survival time was 309 days. Coarsely fractionated radiation therapy may be a reasonable palliative option for dogs with unresectable soft tissue sarcomas, although the response is relatively short-lived.







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Copyright © 2008 by the American Animal Hospital Association.