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Journal of the American Animal Hospital Association 44:139-143 (2008)
© 2008 American Animal Hospital Association

Case Report

Primary Osseous Melanoma in the Tibia of a Dog

Damiano Stefanello, DVM, PhD, Stefano Romussi, DVM, PhD, Paola Signorelli, DVM, PhD, Mario Caniatti, DVM, Diplomate ECVP, Mauro DiGiancamillo, DVM, Paola Roccabianca, DVM, Diplomate ECVP and Giancarlo Avallone, DVM

From the Department of Veterinary Clinical Sciences (Stefanello, Romussi, Signorelli, DiGiancamillo) and the Department of Veterinary Pathology, Hygiene, and Public Health (Caniatti, Roccabianca, Avallone), School of Veterinary Medicine, University of Milan, Via Celoria 10, Milan, 20133, Italy.

An 18-month-old, female Cane Corso dog was presented with a suspected primary tumor of the tibia. Plain radiographs and computed tomography (CT) of the tibia were highly suggestive of a primary bone neoplasm. A diagnosis of malignant melanoma was made by cytology. Total body survey radiographs, CT scan of the thorax, and abdominal ultrasound excluded the presence of neoplastic lesions other than in the tibia. Limb amputation was performed. Histology and immunohistochemical analysis of the tibial neoplasm confirmed the diagnosis of a melanoma with secondary metastasis to the popliteal lymph node. The dog was alive and in good physical condition 43 months after surgery.






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