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Primary Immune-mediated Thrombocytopenia in 30 Dogs (1997–2003)

From the Clinic of Small Animals, Faculty of Veterinary Medicine, Free University of Berlin, Oertzenweg 19b, Berlin, Germany 14163.

During a 6-year period, primary (idiopathic) immune-mediated thrombocytopenia was retrospectively evaluated in 30 dogs. Ages of the dogs ranged from 3 months to 10 years (median 4 years); female dogs were markedly overrepresented with 73%. Clinical examination revealed hemorrhages in 70% of the dogs. Platelet counts ranged from 0 to 111,000/µL (median 8000/µL); 77% of the dogs had platelet counts <30,000/µL. Seventeen dogs were anemic (hematocrit 9% to 36%; median 31%). Immunosuppressive therapy was performed in all but one dog. The recurrence rate of 19 dogs that were followed over an extended period (112 to 1684 days; median 340 days) was 26%. Twenty-nine (97%) dogs survived 14 days after initial presentation, and 27 (93%) dogs survived at least the following 15 to 1684 days (median 220 days).

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				C. Wondratschek, C. Weingart, and B. Kohn Primary Immune-Mediated Thrombocytopenia in Cats J. Am. Anim. Hosp. Assoc., January 1, 2010; 46(1): 12 - 19. [Abstract] [Full Text] [PDF]