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Journal of the American Animal Hospital Association 44:295-301 (2008)
© 2008 American Animal Hospital Association

Exercise-Induced Collapse of Labrador Retrievers: Survey Results and Preliminary Investigation of Heritability

Susan M. Taylor, DVM, Diplomate ACVIM (Internal Medicine), Cindy L. Shmon, DVM, DVSc, Diplomate ACVS (Surgery), G. Diane Shelton, DVM, PhD, Diplomate ACVIM (Internal Medicine), Edward (Ned) E. Patterson, DVM, PhD, Diplomate ACVIM (Internal Medicine), Katie Minor, BS and James R. Mickelson, PhD

From the Department of Small Animal Clinical Sciences (Taylor, Shmon), Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5B4 Canada; the Comparative Neuromuscular Laboratory (Shelton), Department of Pathology, School of Medicine, University of California-San Diego, La Jolla, California 92093-0709; and the Departments of Veterinary Clinical Sciences (Patterson) and Biomedical Sciences (Minor, Mickelson), College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota 55108.

Completed surveys were obtained from owners of 225 Labrador retrievers affected by the syndrome of exercise-induced collapse. Questions addressed signalment, age of onset, description of collapse episodes, and owner perception of activities and factors associated with collapse. Most dogs were young (mean 12 months) when collapse episodes began. Retrieving was the activity most commonly associated with collapse. Owners felt that excitement (187/225; 83%) and high environmental temperatures (71/225; 31%) increased the likelihood of collapse. Analysis of pedigrees collected from 169 affected dogs was most consistent with an autosomal recessive mode of inheritance.




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S. M. Taylor, C. L. Shmon, V. J. Adams, J. R. Mickelson, E. E. Patterson, and G. D. Shelton
Evaluations of Labrador Retrievers With Exercise-Induced Collapse, Including Response to a Standardized Strenuous Exercise Protocol
J. Am. Anim. Hosp. Assoc., January 1, 2009; 45(1): 3 - 13.
[Abstract] [Full Text] [PDF]




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