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Vestibular Syndrome Due to a Choroid Plexus Papilloma in a Ferret

From the Division of Avian and Exotic Animal Medicine (van Zeeland, Schoemaker), Department of Clinical Sciences of Companion Animals, the Department of Pathobiology (Kik), Faculty of Veterinary Medicine, Utrecht University, Utrecht 3584 DS, The Netherlands; Dierenarts Specialisten Amsterdam (Passon-Vastenburg), Weesperzijde 147, Amsterdam, 1091 ET, The Netherlands.

A 6-year-old, castrated male ferret (Mustela putorius furo) was presented with progressive neurological signs consisting of a right-sided head tilt and ataxia. Neurological examination revealed hemiparesis and absence of proprioception on the right side, consistent with central vestibular syndrome. Measurement of blood glucose excluded hypoglycemia due to insulinoma. Contrast-enhanced computed tomography revealed the presence of an intracranial mass, consistent with either granuloma or neoplasia. Palliative treatment with prednisolone yielded no improvement. At postmortem examination, a final diagnosis of a choroid plexus papilloma originating from the fourth ventricle was made. This is the first report of such a tumor in a ferret.