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Journal of the American Animal Hospital Association 41:298-309 (2005)
© 2005 American Animal Hospital Association


Review Article

Nonsteroidal Antiinflammatory Drugs: A Review

Stephen L. Curry, DVM, Steven M. Cogar and James L. Cook, DVM, PhD, Diplomate ACVS

From the Department of Veterinary Medicine and Surgery and the Comparative Orthopaedic Laboratory, College of Veterinary Medicine, University of Missouri, Columbia, Missouri 65211.

The increasing use of nonsteroidal antiinflammatory drugs (NSAIDs) in small animals has resulted in the development of new and innovative additions to this class of drugs. Examples of NSAIDs now available for use in small animals include aspirin, etodolac, carprofen, ketoprofen, meloxicam, deracoxib, and tepoxalin. The purposes of this article are to review the pathophysiology of prostaglandin synthesis and inhibition, the mechanisms of action, pharmacokinetics, pharmacological effects, and potential adverse reactions of aspirin and the newly released NSAIDs.







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Copyright © 2005 by the American Animal Hospital Association.